Manufacturing of Fibrocaps™

The main active components of Fibrocaps™, human thrombin and fibrinogen, are derived from human blood plasma collected in the United States, which has been approved for human use.

During the production of Fibrocaps at the licensed manufacturing site in the UK, fibrinogen and thrombin are stabilized and separately spray-dried to produce soluble free-flowing microparticles. Subsequently, the microparticles are blended in a specific ratio to form a single, ready-to-use dry powder that can be stored at room temperature.

The Fibrocaps powder may be applied to the wound site using a proprietary spray device.



Human fibrinogen and thrombin are spray-dried to form soluble microparticles that are blended to form a dry powder.